Minimally invasive surgery plus alteplase for intracerebral haemorrhage

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منابع مشابه

Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema.

BACKGROUND AND PURPOSE Perihematomal edema (PHE) can worsen outcomes after intracerebral hemorrhage (ICH). Reports suggest that blood degradation products lead to PHE. We hypothesized that hematoma evacuation will reduce PHE volume and that treatment with recombinant tissue-type plasminogen activator (rt-PA) will not exacerbate it. METHODS Minimally invasive surgery and rt-PA in ICH evacuatio...

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Minimally Invasive Surgery for Intracerebral and Intraventricular Hemorrhage

Spontaneous intracerebral hemorrhage (ICH) is the most common type of hemorrhagic stroke, ≈4 times more common than subarachnoid hemorrhage and accounting for 15% of all strokes. ICH is associated with higher rates of morbidity and mortality than all stroke subtypes. Overall, mortality rates for ICH are estimated to be as high as 40% to 50%, with the vast majority of survivors disabled at 6 mon...

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Minimally Invasive Surgery for Spontaneous Supratentorial Intracerebral Hemorrhage

Spontaneous intracerebral hemorrhage is a common subtype of stroke with high incidence rates and mortality worldwide of which over two thirds of deaths are in developing countries, where are >100 000 deaths and approximately 300 000 disabilities annually in China. Supratentorial spontaneous intracerebral hemorrhage (SICH), which accounts for 78% to 88% of intracerebral hemorrhages, is primarily...

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Safety and efficacy of minimally invasive surgery plus recombinant tissue plasminogen activator in intracerebral haemorrhage evacuation (MISTIE): a randomised, phase 2 trial

BACKGROUND Craniotomy, according to the results from trials, does not improve functional outcome after intracerebral haemorrhage. Whether minimally invasive catheter evacuation followed by thrombolysis for clot removal is safe and can achieve a good functional outcome is not known. We investigated the safety and efficacy of alteplase, a recombinant tissue plasminogen activator, in combination w...

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ژورنال

عنوان ژورنال: The Lancet

سال: 2019

ISSN: 0140-6736

DOI: 10.1016/s0140-6736(19)30309-5